Netilmicin is primarily suited for the treatment of dangerous Gram-negative infections , whereby it demonstrates relatively good tolerance. It is particularly indicated for septicemias that have been caused by pseudomonas or gentamicin-resistant germs. In neutropenic patients such a treatment is always combined with a ß-lactam antibiotic. Netilmicin can also be combined with clindamycin or metronidazole for intra-abdominal and gynecological infections. Netilmicin is well suited for the treatment of children with Gram-negative sepsis.
Urinary tract infections should only be treated with oral netilmicin, and only if the problems cannot be solved with better tolerated drugs.
Netilmicin has proven effective against pulmonary infections with cystic fibrosis and - in combination with other antibiotics - against several other infections (e.g. in connection with operations or traumatic wounds, Klebsiella infections). As a rule it is as effective as amikacin or tobramycin.
