Hesperidin

Hesperidin is a bioflavonoid. Bioflavonoids are water-soluble nutrients that are found in some fruits -- especially citrus -- and various leafy green vegetables. Other well known bioflavonoids include quercitin and rutin.

Hesperidin, along with other bioflavanoids, can improve the health of capillaries and connective tissues. Because of this, it has been noted to help with bruising, varicose veins, and fragile capillaries. Other benefits include a purported ablility to alleviate hay fever and other such allergies. Some studies suggest bioflavanoids like hesperidin and quercitin do this by inhibiting the release of histamine. Hesperidin is an important nutrient that works synergistically with Vitamin C to maintain the health of collagen. Sagging and wrinkling of the skin is the consequence of the breakdown of collagen. Precautions: Because it is not considered an essential nutrient, there is no RDA (Recommended Daily Allowance) set. As for dosage amount, it would be generally suggested refraining from using mega-doses -- 500 mgs or above. A dosage of between 10 mgs and 100 mgs seems much more reasonable.