SAFETY DATA SHEET
Date of elaboration : 14/02/02
Updating date : 19/10/05
Name of Product : NETILMICIN SULPHATE
Product not regulated by European directive 2000/32/CE, TPA/Directive 67/548/CE
Label : T R : 61, 20/21/22
S : 45, 36/37/39
Symbols :
F . Easily inflammable X n . Noxious C . Corrosive O . Oxidizer
E . Explosive T . Toxic T+ Very Toxic X i . Irritant |
1. Chemical Identification
*- Trade name : NETILMICIN SULPHATE
*- Supplier : BimSiframGroup
*- Importer : BimSiframGroup- 42 Rue du Faubourg Poissonnière - F.75010 PARIS / FRANCE
*- Emergency tel. N° France : 01 45 42 59 59 (Orfila)
*- Use : Pharmaceutical
2. Composition / Information on Ingredients
*- Chemical name: NETILMICIN SULPHATE
*- Synonyms : Certomycin, Netillin, Netilmicin sulfate, netromycin
*- CAS N° : 56391-57-2
*- EEC N° : 260-147-3
*- Molecular weight : 1442
*- Molecular formula : C42H92N10O34S5
3. Hazards Identification
Symbol : Toxic T
R 61 : May cause harm to the unborn child.
R 20/21/22 : Harmful by inhalation, in contact with skin and if swallowed.
4. First-Aid Measures
*- In case of skin contact: Flush with copious amounts of water for at least 15 minutes. Remove contemned clothing and shoes.
*- In case of contact with eyes: Flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers.
*- In case of inhalation: Remove to fresh air away from exposure site. If breathing become difficult, call a physician.
*- In case of ingestion: Wash out mouth with water provided person is conscious.
In all above cases call a Physician
5. Fire Fighting Measures
*- Extinguishing media: Water spray - carbon dioxide - Dry chemical powder or appropriate foam.
*- Special fire fighting procedures: Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
*- Emits toxic fumes under fire conditions.
6. Accidental Release Measures
*- Wear respirator, chemical safety goggles, rubber boots and heavy rubber gloves.
*- Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pick up is complete.
*- Avoid any penetration in sewerage system or watercourse. In case of penetration alert the authorities.
7. Handling and Storage
*- Handling: Wear appropriate NIOSH/MSHA approved respirator, chemical-resistant gloves, safety goggles, other protective clothing. Mechanical exhaust required.
*- Storage: Store in tightly closed containers in a cool dry place.
*- Wash after handling.
8. Exposure Controls / Personal Protection
See section 7 :
*- Use only in a chemical fume hood
*- Safety shower and eye bath.
9. Physical and Chemical Properties
*- Appearance: Solid
*- Odour: White or yellowish-white
*- Solubility: Very soluble in water, practically insoluble in ether and dehydrate alcohol
*- Specific optical rotation [ a ] D 20 : +88.0 to +96.0
*- pH: 3.5 to 5.5
10. Stability and Reactivity
*- Hazardous combustion or decomposition products: Toxic fumes of carbon monoxide, carbon dioxide, nitrogen oxides, sulphur oxides.
*- Hazardous polymerisation will not occur.
11. Toxicological Information
*- Acute effects : Harmful if swallowed, inhaled, or absorbed through skin.
Prolonged or repeated exposure may cause allergic reactions in certain sensitive individuals.
Aminoglycosides are associated with significant nephrotoxicity and/or ototoxicity.
*- Toxicity data: Oral, rat: LD 50: > 10 mg/Kg; IPR-RAT LD50: 231MG/KG.
*- Other data : for complete data see corresponding articles in the RTECS.
*- RTECS Nr: WK2286000
12. Ecological Information
*- Any flow in the sewerage system or watercourse must be avoided.
*- Data is not yet available.
13. Disposal Considerations
*- Product: In absence of a uniform regulation concerning disposal of chemical products and residues in the EC, they must be considered as special waste. Their disposal is regulated by each member of the EC. We recommend you to contact your local authority; they will inform you about which measures to adopt. Only in case they don't have special measures for this product, you can use this one: dissolve or mix the material with a combustible solvent in a chemical incinerator equipped with an afterburner and scrubber.
*- Packaging: Disposal following the official regulations.
14. Transport information
*- This product is not submitted to transport regulations
15. Regulatory information
*- Label according to EEC - symbol : T - codes : R: 61, 20/21/22 S: 45, 36/37/39
Symbol : Toxic T
R 61 : May cause harm to the unborn child.
R 20/21/22 : Harmful by inhalation, in contact with skin and if swallowed.
S 45 : In case of accident or if you feel unwell, seek medical advice immediately ( show the label where possible ).
S 36/37/39 : Wear suitable protective clothing, gloves and eye/face protection.
*- EEC N° (EINECS) : 260-147-3
*- Product not regulated by European directive 2000/32/CE, Last TPA/Directive 67/548/CE
16. Other information
The above information is based on actual knowledge relatives to the concerned product, on the update date. They are believed to be correct. This sheet is not a guaranty concerning the product properties and shall be used as a guide. Its user has to conformed it self to the whole regulatory texts concerning his activity.
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